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      臨床研究

      原發性肝癌化療栓塞風險的多因素分析

      于杉

      [文章下載]

      【摘要】  【摘要】目的 研究原發性肝癌化療栓塞風險的多因素。方法 研究選擇了我院收治的原發性肝癌患者80例為研究對象。結果 Child-Pugh分級回歸系數為0.862,標準誤為0.741,危險值為7.189,Wald為9.147,P<0.05;

      【關鍵字】  原發性肝癌,化療栓塞術,風險因素

      中圖分類號:文獻標識碼:文章編號:

      [Abstract]Objective To study the multiple factors of chemotherapy and embolization risk of primary liver cancer. Methods Eighty patients with primary liver cancer admitted to our hospital were selected as the research subjects. Results Child-Pugh graded regression coefficient was 0.862, standard error was 0.741, risk value was 7.189, Wald was 9.147, P<0.05; portal vein tumor thrombus regression coefficient was 0.338, standard error was 0.128, risk value was 8.247, and Wald was 6.547. P<0.05; the regression coefficient of iodized oil deposition was 0.448, the standard error was 0.318, the risk value was 7.296, and the Wald was 7.317, P<0.05. Conclusion Patients with primary liver cancer are susceptible to many different factors during chemotherapy embolization. Impacts, which in turn lead to risk issues, require health care providers to provide comprehensive and scientific treatment options that reduce the adverse effects of risk factors on patients.

      原發性肝癌是一種高發性和高病死率的疾病類型,對于人們的身體健康和生命安全產生了嚴重的威脅[1]。肝動脈化療栓塞術是一種介入手術,治療的過程中,可以充分降低患者機體的損傷[2]。但是此種方法使用,容易加劇患者的肝功能損傷[3]。本文主要對原發性肝癌患者化療栓塞風險因素進行研究,具體研究報道如下。 1 資料與方法 1.1 一般資料:本文在研究選擇了我院收治的原發性肝癌患者80例為研究對象,男性患者56例,女性患者24例?;颊吣挲g區間在41~82歲,平均年齡為(61.28±2.15)歲?;颊叩牟〕虖?~5年,平均病程為(3.14±0.11)年。一般資料差異無統計學意義(P>0.05)。 1.2 方法:①使用肝動脈造影和TACE術對患者進行治療[4]。②對患者的肝硬化程度和腫瘤大小進行檢測,注入不同劑量的化學治療藥物,具體分為絲裂霉素、5-氟尿嘧啶、吡柔比星和順鉑等藥物,搭配使用明膠海綿栓塞劑[5]。 1.3 觀察指標:①使用Cox回歸線性分析方程,對患者的 Child-Pugh分級、門靜脈癌栓和碘油沉積情況情況進行計算;②對治療后3年內,患者生存率進行統計。 1.4 統計學方法:應用統計學軟件SPSS24.0。P<0.05,表示組間差異有統計學意義。

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